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• Activity deltas table
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Motif ID: TFAP2{A,C}.p2

Z-value: 5.591

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr9_+_136673534	9.509		COL5A1	collagen, type V, alpha 1
chr9_+_136673464	7.949	NM_000093	COL5A1	collagen, type V, alpha 1
chr15_-_46724360	7.556		FBN1	fibrillin 1
chr17_+_56832255	7.085		TBX2	T-box 2
chr17_+_56831951	6.969	NM_005994	TBX2	T-box 2
chr3_-_126257425	6.423	NM_020733	HEG1	HEG homolog 1 (zebrafish)
chr15_+_64782468	6.277		SMAD6	SMAD family member 6
chr14_+_92049396	5.877	NM_024832	RIN3	Ras and Rab interactor 3
chr2_+_85834111	5.808	NM_032827	ATOH8	atonal homolog 8 (Drosophila)
chr2_+_36436873	5.576	NM_016441	CRIM1	cysteine rich transmembrane BMP regulator 1 (chordin-like)
chr6_+_107917965	5.454	NM_018013	SOBP	sine oculis binding protein homolog (Drosophila)
chr20_+_44771532	5.450	NM_030777	SLC2A10	solute carrier family 2 (facilitated glucose transporter), member 10
chr2_+_159533329	5.443	NM_001145909 NM_033394	TANC1	tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1
chr9_-_83493415	5.288	NM_005077	TLE1	transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
chr14_-_24588916	5.207	NM_014178	STXBP6	syntaxin binding protein 6 (amisyn)
chr3_-_130807865	5.169	NM_015103	PLXND1	plexin D1
chr19_+_39664706	5.167	NM_001080436	WTIP	Wilms tumor 1 interacting protein
chr5_+_92946348	5.088		NR2F1	nuclear receptor subfamily 2, group F, member 1
chr15_-_53667800	4.989		PYGO1	pygopus homolog 1 (Drosophila)
chr19_+_15079141	4.972	NM_033025	SYDE1	synapse defective 1, Rho GTPase, homolog 1 (C. elegans)
chr18_-_53621277	4.934	NM_005603	ATP8B1	ATPase, aminophospholipid transporter, class I, type 8B, member 1
chr3_+_51403760	4.872	NM_013286	RBM15B	RNA binding motif protein 15B
chr10_-_76829857	4.832		ZNF503	zinc finger protein 503
chr8_+_37672427	4.737	NM_025069	ZNF703	zinc finger protein 703
chr8_-_38444982	4.714		FGFR1	fibroblast growth factor receptor 1
chr22_-_19122107	4.472	NM_153334 NM_182895	SCARF2	scavenger receptor class F, member 2
chr2_+_205118710	4.446	NM_057177 NM_152526 NM_205863	PARD3B	par-3 partitioning defective 3 homolog B (C. elegans)
chr4_+_72271218	4.427	NM_001098484 NM_001134742	SLC4A4	solute carrier family 4, sodium bicarbonate cotransporter, member 4
chr17_+_56832492	4.338		TBX2	T-box 2
chr1_-_94779727	4.216	NM_001178096 NM_001993	F3	coagulation factor III (thromboplastin, tissue factor)
chr12_-_105165805	4.195	NM_006825	CKAP4	cytoskeleton-associated protein 4
chr17_-_72218661	4.174		MXRA7	matrix-remodelling associated 7
chr2_+_36436316	4.134		CRIM1	cysteine rich transmembrane BMP regulator 1 (chordin-like)
chr14_-_29466562	4.118	NM_002742	PRKD1	protein kinase D1
chr11_-_124175467	4.041		C11orf61	chromosome 11 open reading frame 61
chr2_+_235525355	4.021	NM_014521	SH3BP4	SH3-domain binding protein 4
chr3_+_44878380	3.976	NM_144638	TMEM42	transmembrane protein 42
chr1_+_33494745	3.967	NM_152493	ZNF362	zinc finger protein 362
chr12_+_2032649	3.960	NM_000719 NM_001129827 NM_001129829 NM_001129830 NM_001129831 NM_001129832 NM_001129833 NM_001129834 NM_001129835 NM_001129836 NM_001129837 NM_001129838 NM_001129839 NM_001129840 NM_001129841 NM_001129842 NM_001129843 NM_001129844 NM_001129846 NM_001167623 NM_001167624 NM_001167625 NM_199460	CACNA1C	calcium channel, voltage-dependent, L type, alpha 1C subunit
chr6_+_1336077	3.959
chr11_-_60819110	3.946		VWCE	von Willebrand factor C and EGF domains
chr7_+_288051	3.920	NM_020223	FAM20C	family with sequence similarity 20, member C
chr15_+_89228668	3.910	NM_001143785 NM_002005	FES	feline sarcoma oncogene
chr1_-_85703198	3.905		DDAH1	dimethylarginine dimethylaminohydrolase 1
chr16_-_71639670	3.876	NM_006885	ZFHX3	zinc finger homeobox 3
chr16_+_85158357	3.819	NM_005251	FOXC2	forkhead box C2 (MFH-1, mesenchyme forkhead 1)
chr5_+_98132898	3.801	NM_001012761	RGMB	RGM domain family, member B
chrX_+_149282097	3.789	NM_001177465	MAMLD1	mastermind-like domain containing 1
chr17_+_35751796	3.749	NM_001024809	RARA	retinoic acid receptor, alpha
chr2_+_42128521	3.748	NM_138370	PKDCC	protein kinase domain containing, cytoplasmic homolog (mouse)
chr16_-_71650034	3.737	NM_001164766	ZFHX3	zinc finger homeobox 3
chr9_-_37566248	3.721	NM_012166	FBXO10	F-box protein 10
chr11_-_124175493	3.711	NM_024631	C11orf61	chromosome 11 open reading frame 61
chr12_-_105056577	3.682		NUAK1	NUAK family, SNF1-like kinase, 1
chrX_-_54538591	3.649		FGD1	FYVE, RhoGEF and PH domain containing 1
chr11_-_60819273	3.624	NM_152718	VWCE	von Willebrand factor C and EGF domains
chr6_+_19945578	3.616	NM_001546	ID4	inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
chr2_+_205118961	3.609		PARD3B	par-3 partitioning defective 3 homolog B (C. elegans)
chr14_+_54102518	3.580		LOC644925	hypothetical LOC644925
chr2_+_205118801	3.575		PARD3B	par-3 partitioning defective 3 homolog B (C. elegans)
chr5_+_129268352	3.498	NM_175856	CHSY3	chondroitin sulfate synthase 3
chr3_+_112273352	3.493		PVRL3	poliovirus receptor-related 3
chr4_+_108965167	3.463	NM_001136258	SGMS2	sphingomyelin synthase 2
chr3_-_151171190	3.458	NM_002628 NM_053024	PFN2	profilin 2
chr6_-_132314004	3.455	NM_001901	CTGF	connective tissue growth factor
chr20_+_4077466	3.454		SMOX	spermine oxidase
chr3_+_112273464	3.442	NM_015480	PVRL3	poliovirus receptor-related 3
chr8_-_38444675	3.412		FGFR1	fibroblast growth factor receptor 1
chr2_+_109112428	3.394	NM_001099289	SH3RF3	SH3 domain containing ring finger 3
chrX_+_9943793	3.380	NM_015691	WWC3	WWC family member 3
chr7_+_94374862	3.372	NM_001166160 NM_017650	PPP1R9A	protein phosphatase 1, regulatory (inhibitor) subunit 9A
chr17_+_1906262	3.361	NM_001098202	HIC1	hypermethylated in cancer 1
chr7_-_27136876	3.360	NM_002141	HOXA4	homeobox A4
chr9_+_98252200	3.321	NM_014282	HABP4	hyaluronan binding protein 4
chr9_+_128128913	3.320	NM_001011703 NM_033446	FAM125B	family with sequence similarity 125, member B
chr2_-_197165495	3.316	NM_020760	HECW2	HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2
chr19_-_54557450	3.297	NM_003598	TEAD2	TEA domain family member 2
chr10_+_123862430	3.225		TACC2	transforming, acidic coiled-coil containing protein 2
chr5_-_178704934	3.215		ADAMTS2	ADAM metallopeptidase with thrombospondin type 1 motif, 2
chr1_-_212791467	3.206		PTPN14	protein tyrosine phosphatase, non-receptor type 14
chr21_-_27139143	3.193		ADAMTS1	ADAM metallopeptidase with thrombospondin type 1 motif, 1
chr5_-_159672060	3.180	NM_024565	CCNJL	cyclin J-like
chr13_+_109757593	3.175	NM_001846	COL4A2	collagen, type IV, alpha 2
chr4_-_141896920	3.144	NM_015130	TBC1D9	TBC1 domain family, member 9 (with GRAM domain)
chr18_+_18969724	3.124	NM_001100619	CABLES1	Cdk5 and Abl enzyme substrate 1
chr6_-_128883125	3.120	NM_002844 NM_001135648	PTPRK	protein tyrosine phosphatase, receptor type, K
chr9_+_115958051	3.098	NM_032888	COL27A1	collagen, type XXVII, alpha 1
chr10_+_124124196	3.093		PLEKHA1	pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1
chr8_-_93184629	3.074	NM_001198633 NM_175634	RUNX1T1	runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr17_-_53387493	3.070		CUEDC1	CUE domain containing 1
chr7_-_5427367	3.050
chr5_+_34692124	3.042	NM_001145522 NM_015577	RAI14	retinoic acid induced 14
chr16_+_88517187	3.042	NM_006086	TUBB3	tubulin, beta 3
chr6_+_157141565	3.019		ARID1B	AT rich interactive domain 1B (SWI1-like)
chr1_+_9275542	3.019		SPSB1	splA/ryanodine receptor domain and SOCS box containing 1
chr17_+_52026058	3.006	NM_005450	NOG	noggin
chr2_-_175255717	2.996	NM_001077269	WIPF1	WAS/WASL interacting protein family, member 1
chr17_-_72218535	2.979	NM_001008528 NM_001008529 NM_198530	MXRA7	matrix-remodelling associated 7
chr13_-_109757442	2.973	NM_001845	COL4A1	collagen, type IV, alpha 1
chr3_-_129689394	2.972	NM_001145662	GATA2	GATA binding protein 2
chr7_-_45927263	2.971	NM_000598 NM_001013398	IGFBP3	insulin-like growth factor binding protein 3
chr7_+_288195	2.956		FAM20C	family with sequence similarity 20, member C
chr15_+_66658626	2.952	NM_006091	CORO2B	coronin, actin binding protein, 2B
chr13_+_97593711	2.947		FARP1	FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
chr5_-_57791544	2.938	NM_006622	PLK2	polo-like kinase 2
chr3_-_151171576	2.935		PFN2	profilin 2
chr13_-_36392370	2.922	NM_001127217 NM_005905	SMAD9	SMAD family member 9
chr9_-_38059082	2.922		SHB	Src homology 2 domain containing adaptor protein B
chr12_-_94708477	2.915		NTN4	netrin 4
chr8_-_48813256	2.913	NM_005195	CEBPD	CCAAT/enhancer binding protein (C/EBP), delta
chr20_+_11819364	2.884	NM_181443	BTBD3	BTB (POZ) domain containing 3
chr5_+_34692352	2.883	NM_001145520	RAI14	retinoic acid induced 14
chr5_-_178705036	2.849	NM_014244 NM_021599	ADAMTS2	ADAM metallopeptidase with thrombospondin type 1 motif, 2
chr5_+_34692239	2.839		RAI14	retinoic acid induced 14
chr10_-_76831545	2.839		ZNF503	zinc finger protein 503
chr10_-_76831430	2.838	NM_032772	ZNF503	zinc finger protein 503
chr1_-_95165037	2.832		CNN3	calponin 3, acidic
chr10_-_725522	2.826	NM_014974	DIP2C	DIP2 disco-interacting protein 2 homolog C (Drosophila)
chr13_+_30378311	2.823	NM_032849	C13orf33	chromosome 13 open reading frame 33
chr8_+_30361485	2.821	NM_001008710 NM_001008711 NM_001008712 NM_006867	RBPMS	RNA binding protein with multiple splicing
chr3_+_171558188	2.819		SKIL	SKI-like oncogene
chr1_+_9275518	2.813	NM_025106	SPSB1	splA/ryanodine receptor domain and SOCS box containing 1
chr10_-_118491971	2.812	NM_025015	HSPA12A	heat shock 70kDa protein 12A
chr8_-_48813236	2.797		CEBPD	CCAAT/enhancer binding protein (C/EBP), delta
chr12_-_94708641	2.793	NM_021229	NTN4	netrin 4
chr3_+_160964574	2.793		SCHIP1	schwannomin interacting protein 1
chr22_-_19122047	2.789		SCARF2	scavenger receptor class F, member 2
chr2_+_241586927	2.785	NM_001080437	SNED1	sushi, nidogen and EGF-like domains 1
chr10_-_76831142	2.779		ZNF503	zinc finger protein 503
chr8_-_38444398	2.743	NM_001174065 NM_001174066 NM_001174067	FGFR1	fibroblast growth factor receptor 1
chr2_+_42129440	2.724
chr2_-_45090025	2.712	NM_016932	SIX2	SIX homeobox 2
chr3_+_189354167	2.686	NM_001167672	LPP	LIM domain containing preferred translocation partner in lipoma
chr4_-_22126437	2.668	NM_145290	GPR125	G protein-coupled receptor 125
chr12_-_15833617	2.666	NM_004447	EPS8	epidermal growth factor receptor pathway substrate 8
chr2_+_241023908	2.666		GPC1	glypican 1
chr19_-_15172773	2.633	NM_000435	NOTCH3	notch 3
chr6_+_151603346	2.627		AKAP12	A kinase (PRKA) anchor protein 12
chr12_+_79995927	2.621	NM_024560	ACSS3	acyl-CoA synthetase short-chain family member 3
chr10_+_116571485	2.619	NM_001135051 NM_020940	FAM160B1	family with sequence similarity 160, member B1
chr22_-_32646325	2.606	NM_004737 NM_133642	LARGE	like-glycosyltransferase
chr7_-_122313646	2.594		CADPS2	Ca++-dependent secretion activator 2
chr9_-_135847106	2.585	NM_001134398 NM_003371	VAV2	vav 2 guanine nucleotide exchange factor
chr5_+_60663842	2.577	NM_020928	ZSWIM6	zinc finger, SWIM-type containing 6
chr19_+_1200882	2.573		MIDN	midnolin
chr5_+_72957736	2.568	NM_001080479 NM_001177693	RGNEF	190 kDa guanine nucleotide exchange factor
chr8_+_37773991	2.565		GPR124	G protein-coupled receptor 124
chr21_-_27139563	2.559	NM_006988	ADAMTS1	ADAM metallopeptidase with thrombospondin type 1 motif, 1
chr15_+_30797466	2.549	NM_001191322 NM_001191323 NM_013372	GREM1	gremlin 1
chr18_+_2896956	2.512		EMILIN2	elastin microfibril interfacer 2
chr17_-_1306160	2.512	NM_005206 NM_016823	CRK	v-crk sarcoma virus CT10 oncogene homolog (avian)
chr3_-_121652183	2.494	NM_007085	FSTL1	follistatin-like 1
chr8_-_18915443	2.471	NM_015310	PSD3	pleckstrin and Sec7 domain containing 3
chr2_-_127580975	2.468	NM_004305 NM_139343 NM_139344 NM_139345 NM_139346 NM_139347 NM_139348 NM_139349 NM_139350 NM_139351	BIN1	bridging integrator 1
chr1_-_32940943	2.462	NM_001161708 NM_030786	SYNC	syncoilin, intermediate filament protein
chr7_-_139987044	2.437		DENND2A	DENN/MADD domain containing 2A
chr10_+_104394185	2.434	NM_030912	TRIM8	tripartite motif containing 8
chr20_-_4177519	2.433	NM_000678	ADRA1D	adrenergic, alpha-1D-, receptor
chr1_+_199884152	2.417		NAV1	neuron navigator 1
chr17_+_17525571	2.416
chr11_-_65841077	2.402	NM_020404	CD248	CD248 molecule, endosialin
chr14_+_51188289	2.398	NM_152330	FRMD6	FERM domain containing 6
chr16_-_69277194	2.396		MTSS1L	metastasis suppressor 1-like
chr4_+_151218862	2.396	NM_001040260 NM_001040261	DCLK2	doublecortin-like kinase 2
chr10_-_105410840	2.390
chr15_-_53822468	2.386	NM_173814	PRTG	protogenin
chr6_-_117193505	2.380	NM_001085480	FAM162B	family with sequence similarity 162, member B
chr5_-_121441866	2.378		LOX	lysyl oxidase
chr19_+_16296632	2.373	NM_016270	KLF2	Kruppel-like factor 2 (lung)
chr10_+_59942874	2.362	NM_001080512	BICC1	bicaudal C homolog 1 (Drosophila)
chr14_-_102593384	2.361	NM_006035	CDC42BPB	CDC42 binding protein kinase beta (DMPK-like)
chr11_-_65396775	2.358	NM_016938	EFEMP2	EGF containing fibulin-like extracellular matrix protein 2
chr10_+_128583984	2.347	NM_001380	DOCK1	dedicator of cytokinesis 1
chr17_-_19711580	2.345	NM_001142610 NM_014683	ULK2	unc-51-like kinase 2 (C. elegans)
chr10_+_122206455	2.341	NM_001030059	PPAPDC1A	phosphatidic acid phosphatase type 2 domain containing 1A
chr16_-_69277355	2.339	NM_138383	MTSS1L	metastasis suppressor 1-like
chr15_+_65145215	2.333		SMAD3	SMAD family member 3
chr2_-_144991386	2.331		ZEB2	zinc finger E-box binding homeobox 2
chr20_+_8060762	2.320	NM_015192 NM_182734	PLCB1	phospholipase C, beta 1 (phosphoinositide-specific)
chr4_-_158111995	2.314	NM_016205	PDGFC	platelet derived growth factor C
chr12_+_2032964	2.312		CACNA1C	calcium channel, voltage-dependent, L type, alpha 1C subunit
chr6_+_3696224	2.306
chr10_-_100017933	2.298	NM_032211	LOXL4	lysyl oxidase-like 4
chr22_-_34754343	2.292	NM_001082578 NM_001082579	RBFOX2	RNA binding protein, fox-1 homolog (C. elegans) 2
chr10_+_94439658	2.289	NM_002729	HHEX	hematopoietically expressed homeobox
chr14_+_99329198	2.287	NM_001008707 NM_004434	EML1	echinoderm microtubule associated protein like 1
chr15_-_58671929	2.282	NM_134262	RORA	RAR-related orphan receptor A
chr16_-_88084387	2.275	NM_013275	ANKRD11	ankyrin repeat domain 11
chr2_+_236068029	2.255		AGAP1	ArfGAP with GTPase domain, ankyrin repeat and PH domain 1
chr11_-_1549719	2.255	NM_004420	DUSP8	dual specificity phosphatase 8
chr19_+_1199548	2.254	NM_177401	MIDN	midnolin
chr9_-_25668230	2.244		TUSC1	tumor suppressor candidate 1
chr14_+_68796621	2.238		GALNTL1	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 1
chr15_+_72006015	2.238		LOXL1	lysyl oxidase-like 1
chr9_-_38059207	2.235	NM_003028	SHB	Src homology 2 domain containing adaptor protein B
chr13_+_26029799	2.234	NM_006646	WASF3	WAS protein family, member 3
chr1_+_179148935	2.230	NM_020950	KIAA1614	KIAA1614
chr6_+_1335067	2.228	NM_001452	FOXF2	forkhead box F2
chr2_+_54536780	2.222	NM_003128	SPTBN1	spectrin, beta, non-erythrocytic 1
chr5_-_107744971	2.213		FBXL17	F-box and leucine-rich repeat protein 17

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.08	2.09e-29	GO:0009987	cellular process
1.19	1.07e-27	GO:0044260	cellular macromolecule metabolic process
1.13	4.32e-22	GO:0044237	cellular metabolic process
1.15	7.76e-20	GO:0043170	macromolecule metabolic process
1.22	1.26e-17	GO:0044267	cellular protein metabolic process
1.11	2.93e-17	GO:0008152	metabolic process
1.12	4.89e-17	GO:0044238	primary metabolic process
1.10	1.56e-13	GO:0050794	regulation of cellular process
1.19	6.79e-13	GO:0071842	cellular component organization at cellular level
1.16	2.37e-12	GO:0016043	cellular component organization
1.18	3.12e-12	GO:0071841	cellular component organization or biogenesis at cellular level
1.09	4.49e-12	GO:0050789	regulation of biological process
1.15	1.40e-11	GO:0071840	cellular component organization or biogenesis
1.23	1.91e-11	GO:0006996	organelle organization
1.08	4.11e-11	GO:0065007	biological regulation
1.17	5.43e-11	GO:0006139	nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.19	8.61e-11	GO:0048523	negative regulation of cellular process
1.16	1.17e-10	GO:0019538	protein metabolic process
1.20	2.52e-10	GO:0043412	macromolecule modification
1.20	4.24e-10	GO:0006464	protein modification process
1.17	4.37e-09	GO:0048519	negative regulation of biological process
1.26	8.00e-09	GO:0007049	cell cycle
1.16	1.00e-08	GO:0048522	positive regulation of cellular process
1.16	1.92e-07	GO:0090304	nucleic acid metabolic process
1.13	2.04e-07	GO:0006807	nitrogen compound metabolic process
1.19	2.28e-07	GO:0023051	regulation of signaling
1.13	2.87e-07	GO:0034641	cellular nitrogen compound metabolic process
1.20	4.88e-07	GO:0009966	regulation of signal transduction
1.43	1.02e-06	GO:0051325	interphase
1.43	1.39e-06	GO:0051329	interphase of mitotic cell cycle
1.14	2.03e-06	GO:0048518	positive regulation of biological process
1.31	2.27e-06	GO:0000278	mitotic cell cycle
1.21	4.34e-06	GO:0044248	cellular catabolic process
1.26	4.39e-06	GO:0051128	regulation of cellular component organization
1.17	6.53e-06	GO:0009059	macromolecule biosynthetic process
1.17	1.13e-05	GO:0034645	cellular macromolecule biosynthetic process
1.18	1.40e-05	GO:0007399	nervous system development
1.25	2.31e-05	GO:0022402	cell cycle process
1.19	4.08e-05	GO:0035556	intracellular signal transduction
1.27	7.19e-05	GO:0051726	regulation of cell cycle
1.23	7.32e-05	GO:0048699	generation of neurons
1.22	8.50e-05	GO:0022008	neurogenesis
1.21	1.45e-04	GO:0032268	regulation of cellular protein metabolic process
1.09	1.48e-04	GO:0051716	cellular response to stimulus
1.25	1.50e-04	GO:0022403	cell cycle phase
1.15	1.69e-04	GO:0010467	gene expression
1.10	4.29e-04	GO:0032502	developmental process
1.17	5.35e-04	GO:0033036	macromolecule localization
1.15	5.91e-04	GO:0016070	RNA metabolic process
1.10	6.40e-04	GO:0031323	regulation of cellular metabolic process
1.18	6.61e-04	GO:0010604	positive regulation of macromolecule metabolic process
1.12	6.80e-04	GO:0044249	cellular biosynthetic process
1.28	6.89e-04	GO:0007010	cytoskeleton organization
1.19	7.52e-04	GO:0008104	protein localization
1.32	7.95e-04	GO:0007264	small GTPase mediated signal transduction
1.39	8.43e-04	GO:0030036	actin cytoskeleton organization
1.20	8.56e-04	GO:0006793	phosphorus metabolic process
1.20	8.56e-04	GO:0006796	phosphate metabolic process
1.19	9.75e-04	GO:0051246	regulation of protein metabolic process
1.31	1.01e-03	GO:0051247	positive regulation of protein metabolic process
1.21	1.11e-03	GO:0010605	negative regulation of macromolecule metabolic process
1.34	1.12e-03	GO:0033043	regulation of organelle organization
1.31	1.41e-03	GO:0032270	positive regulation of cellular protein metabolic process
1.40	1.48e-03	GO:0051129	negative regulation of cellular component organization
1.32	1.48e-03	GO:0044419	interspecies interaction between organisms
1.10	1.91e-03	GO:0007275	multicellular organismal development
1.26	1.94e-03	GO:0044265	cellular macromolecule catabolic process
1.24	1.96e-03	GO:0007167	enzyme linked receptor protein signaling pathway
1.10	2.06e-03	GO:0007165	signal transduction
1.22	2.28e-03	GO:2000026	regulation of multicellular organismal development
1.18	2.44e-03	GO:0010941	regulation of cell death
1.09	2.52e-03	GO:0019222	regulation of metabolic process
1.35	2.73e-03	GO:0030029	actin filament-based process
1.21	2.82e-03	GO:0033554	cellular response to stress
1.17	2.87e-03	GO:0031325	positive regulation of cellular metabolic process
1.17	3.04e-03	GO:0009893	positive regulation of metabolic process
1.38	3.28e-03	GO:0046578	regulation of Ras protein signal transduction
1.11	3.33e-03	GO:0048731	system development
1.18	3.43e-03	GO:0043067	regulation of programmed cell death
1.23	4.35e-03	GO:0045595	regulation of cell differentiation
1.09	4.37e-03	GO:0080090	regulation of primary metabolic process
1.31	4.74e-03	GO:0010564	regulation of cell cycle process
1.10	4.76e-03	GO:0048856	anatomical structure development
1.13	5.28e-03	GO:0048583	regulation of response to stimulus
1.11	5.34e-03	GO:0009058	biosynthetic process
1.22	5.68e-03	GO:0030182	neuron differentiation
1.19	6.69e-03	GO:0050793	regulation of developmental process
1.33	6.81e-03	GO:0031401	positive regulation of protein modification process
1.20	6.85e-03	GO:0045184	establishment of protein localization
1.18	7.34e-03	GO:0042981	regulation of apoptosis
1.23	7.50e-03	GO:0009057	macromolecule catabolic process
1.30	7.61e-03	GO:0051056	regulation of small GTPase mediated signal transduction
1.18	7.61e-03	GO:0009892	negative regulation of metabolic process
1.19	7.65e-03	GO:0031324	negative regulation of cellular metabolic process
1.31	8.60e-03	GO:0009894	regulation of catabolic process
1.19	8.67e-03	GO:0048468	cell development
1.17	9.21e-03	GO:0010646	regulation of cell communication
1.26	9.90e-03	GO:0000904	cell morphogenesis involved in differentiation
1.37	1.12e-02	GO:0071156	regulation of cell cycle arrest
1.14	1.22e-02	GO:0009653	anatomical structure morphogenesis
1.15	1.43e-02	GO:0009056	catabolic process
1.21	1.51e-02	GO:0006468	protein phosphorylation
1.08	1.61e-02	GO:0023052	signaling
1.19	1.62e-02	GO:0015031	protein transport
1.09	1.67e-02	GO:0060255	regulation of macromolecule metabolic process
1.20	1.96e-02	GO:0012501	programmed cell death
1.22	2.00e-02	GO:0051276	chromosome organization
1.19	2.05e-02	GO:0008219	cell death
1.48	2.14e-02	GO:0010639	negative regulation of organelle organization
1.19	2.39e-02	GO:0016310	phosphorylation
1.19	2.51e-02	GO:0031399	regulation of protein modification process
1.18	2.76e-02	GO:0016265	death
1.17	3.03e-02	GO:0006357	regulation of transcription from RNA polymerase II promoter
1.44	3.18e-02	GO:0000082	G1/S transition of mitotic cell cycle
1.15	3.33e-02	GO:0051641	cellular localization
1.30	3.61e-02	GO:0060284	regulation of cell development
1.31	3.91e-02	GO:0031329	regulation of cellular catabolic process
1.36	4.03e-02	GO:0000075	cell cycle checkpoint

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.09	1.97e-42	GO:0005622	intracellular
1.09	1.59e-41	GO:0044424	intracellular part
1.12	1.38e-32	GO:0005737	cytoplasm
1.10	4.13e-28	GO:0043226	organelle
1.10	6.36e-28	GO:0043229	intracellular organelle
1.11	4.23e-27	GO:0043227	membrane-bounded organelle
1.10	8.98e-27	GO:0043231	intracellular membrane-bounded organelle
1.13	1.22e-22	GO:0044444	cytoplasmic part
1.13	9.65e-18	GO:0044422	organelle part
1.23	1.00e-17	GO:0005829	cytosol
1.13	2.20e-17	GO:0044446	intracellular organelle part
1.12	1.75e-15	GO:0005634	nucleus
1.20	1.44e-12	GO:0044428	nuclear part
1.17	6.94e-10	GO:0070013	intracellular organelle lumen
1.17	1.57e-09	GO:0031974	membrane-enclosed lumen
1.19	3.59e-09	GO:0031981	nuclear lumen
1.16	4.04e-09	GO:0043233	organelle lumen
1.13	4.90e-09	GO:0032991	macromolecular complex
1.13	7.48e-08	GO:0043234	protein complex
1.02	1.16e-06	GO:0005623	cell
1.02	1.37e-06	GO:0044464	cell part
1.16	9.05e-06	GO:0012505	endomembrane system
1.18	1.03e-05	GO:0005654	nucleoplasm
1.12	5.21e-05	GO:0043228	non-membrane-bounded organelle
1.12	5.21e-05	GO:0043232	intracellular non-membrane-bounded organelle
1.12	5.66e-04	GO:0031090	organelle membrane
1.42	8.58e-04	GO:0031252	cell leading edge
1.46	2.81e-03	GO:0031301	integral to organelle membrane
1.17	3.04e-03	GO:0005794	Golgi apparatus
1.31	3.13e-03	GO:0015629	actin cytoskeleton
1.23	3.38e-03	GO:0005694	chromosome
1.24	6.08e-03	GO:0044427	chromosomal part
1.39	1.75e-02	GO:0031300	intrinsic to organelle membrane
1.31	2.54e-02	GO:0005635	nuclear envelope
1.39	4.37e-02	GO:0000151	ubiquitin ligase complex
1.17	4.86e-02	GO:0031967	organelle envelope

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.14	1.17e-31	GO:0005515	protein binding
1.06	1.31e-20	GO:0005488	binding
1.17	5.19e-10	GO:0000166	nucleotide binding
1.19	1.60e-09	GO:0035639	purine ribonucleoside triphosphate binding
1.19	2.41e-09	GO:0017076	purine nucleotide binding
1.18	5.55e-09	GO:0032553	ribonucleotide binding
1.18	5.55e-09	GO:0032555	purine ribonucleotide binding
1.18	1.02e-06	GO:0030554	adenyl nucleotide binding
1.18	1.04e-06	GO:0005524	ATP binding
1.26	1.32e-06	GO:0019899	enzyme binding
1.18	2.21e-06	GO:0032559	adenyl ribonucleotide binding
1.32	4.57e-06	GO:0030695	GTPase regulator activity
1.33	4.75e-06	GO:0004674	protein serine/threonine kinase activity
1.08	7.19e-06	GO:0003824	catalytic activity
1.31	7.84e-06	GO:0060589	nucleoside-triphosphatase regulator activity
1.22	2.48e-05	GO:0016772	transferase activity, transferring phosphorus-containing groups
1.27	1.65e-04	GO:0008092	cytoskeletal protein binding
1.36	2.31e-04	GO:0005083	small GTPase regulator activity
1.21	4.19e-04	GO:0016301	kinase activity
1.22	4.83e-04	GO:0016773	phosphotransferase activity, alcohol group as acceptor
1.86	7.12e-04	GO:0046332	SMAD binding
1.24	9.58e-04	GO:0004672	protein kinase activity
1.18	2.01e-03	GO:0030528	transcription regulator activity
1.13	2.31e-03	GO:0016740	transferase activity
1.18	3.36e-03	GO:0030234	enzyme regulator activity
2.21	4.67e-03	GO:0004675	transmembrane receptor protein serine/threonine kinase activity
1.29	9.41e-03	GO:0003779	actin binding
2.19	2.27e-02	GO:0005024	transforming growth factor beta receptor activity
1.39	2.50e-02	GO:0005085	guanyl-nucleotide exchange factor activity
1.15	3.98e-02	GO:0001071	nucleic acid binding transcription factor activity
1.15	3.98e-02	GO:0003700	sequence-specific DNA binding transcription factor activity